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Norihito Shintani Selected Research

Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)

4/2020Pituitary Adenylate Cyclase-Activating Polypeptide in the Ventromedial Hypothalamus Is Responsible for Food Intake Behavior by Modulating the Expression of Agouti-Related Peptide in Mice.
1/2019Pituitary Adenylate Cyclase-Activating Polypeptide Modulates Dendritic Spine Maturation and Morphogenesis via MicroRNA-132 Upregulation.
1/2016High-Fat Diet Augments VPAC1 Receptor-Mediated PACAP Action on the Liver, Inducing LAR Expression and Insulin Resistance.
1/2016PACAP suppresses dry eye signs by stimulating tear secretion.
7/2015Comparative gene expression profiles in pancreatic islets associated with agouti yellow mutation and PACAP overexpression in mice.
10/2014An enriched environment ameliorates memory impairments in PACAP-deficient mice.
1/2014Increased behavioral and neuronal responses to a hallucinogenic drug in PACAP heterozygous mutant mice.
2/2013The selective metabotropic glutamate 2/3 receptor agonist MGS0028 reverses psychomotor abnormalities and recognition memory deficits in mice lacking the pituitary adenylate cyclase-activating polypeptide.
11/2012Compensatory recovery of blood glucose levels in KKA(y) mice fed a high-fat diet: insulin-sparing effects of PACAP overexpression in β cells.
11/2012Neuroprotective effect of endogenous pituitary adenylate cyclase-activating polypeptide on spinal cord injury.
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Norihito Shintani Research Topics

Disease

9Schizophrenia (Dementia Praecox)
01/2019 - 01/2010
6Mental Disorders (Mental Disorder)
01/2019 - 01/2012
4Body Weight (Weight, Body)
04/2020 - 12/2004
3Insulin Resistance
01/2016 - 05/2008
3Hyperinsulinism (Hyperinsulinemia)
07/2015 - 05/2004
3Hyperplasia
07/2015 - 05/2004
3Hypothermia
01/2014 - 01/2010
3Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
02/2013 - 11/2003
3Ischemia
11/2010 - 05/2006
2Intellectual Disability (Idiocy)
01/2020 - 03/2004
2Autistic Disorder (Autism)
11/2019 - 01/2016
2Cognitive Dysfunction
11/2016 - 10/2014
2Diabetes Mellitus
07/2015 - 01/2011
2Neoplasms (Cancer)
05/2015 - 02/2014
2Pancreatitis
01/2011 - 08/2009
2Edema (Dropsy)
01/2010 - 08/2009
2Infarction (Infarctions)
01/2010 - 05/2006
2Inflammation (Inflammations)
08/2009 - 07/2008
2Obesity
05/2008 - 05/2004
1Infections
04/2020
1Neurodevelopmental Disorders
01/2020
1Autism Spectrum Disorder
01/2020
1Nervous System Diseases (Neurological Disorders)
01/2019
1Parkinsonian Disorders (Parkinsonism)
01/2018
1Treatment-Resistant Schizophrenia
01/2017
1Neuroblastoma
03/2016
1Hypersensitivity (Allergy)
01/2016
1Dry Eye Syndromes (Dry Eye Syndrome)
01/2016
1Anorexia
02/2014
1Memory Disorders (Memory Loss)
02/2013
1Contusions
11/2012
1Hyperglycemia
11/2012
1Type 2 Diabetes Mellitus (MODY)
11/2012
1Spinal Cord Injuries (Spinal Cord Injury)
11/2012
1Retinal Diseases
11/2010
1Hypoxia (Hypoxemia)
11/2010
1Retinal Neovascularization
11/2010
1Diabetic Retinopathy (Retinopathy, Diabetic)
11/2010
1Wounds and Injuries (Trauma)
11/2010
1Cardiomyopathies (Cardiomyopathy)
06/2010
1Fibrosis (Cirrhosis)
06/2010
1Major Depressive Disorder (Major Depressive Disorders)
01/2010
1Brain Ischemia (Cerebral Ischemia)
01/2010
1Alcoholism (Alcohol Abuse)
01/2010
1Brain Edema (Cerebral Edema)
01/2010
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/2010
1Necrosis
08/2009
1Chronic Pancreatitis
08/2009

Drug/Important Bio-Agent (IBA)

32Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)IBA
04/2020 - 11/2003
4Glucose (Dextrose)FDA LinkGeneric
01/2016 - 05/2008
3Pituitary Adenylate Cyclase-Activating Polypeptide ReceptorsIBA
04/2020 - 11/2004
3NeuropeptidesIBA
01/2019 - 06/2010
3N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
11/2016 - 08/2004
3Insulin (Novolin)FDA Link
01/2016 - 05/2008
3Messenger RNA (mRNA)IBA
11/2010 - 03/2004
2Proteins (Proteins, Gene)FDA Link
01/2018 - 08/2009
2Clozapine (Clozaril)FDA LinkGeneric
01/2017 - 11/2012
2Antipsychotic Agents (Antipsychotics)IBA
01/2017 - 11/2012
2EnzymesIBA
11/2016 - 01/2011
2LipopolysaccharidesIBA
05/2015 - 02/2014
2ramatrobanIBA
05/2015 - 02/2014
2Pharmaceutical PreparationsIBA
05/2015 - 01/2011
2CorticosteroneIBA
05/2015 - 01/2014
2CeruletideIBA
01/2011 - 08/2009
2Ethanol (Ethyl Alcohol)IBA
01/2010 - 07/2006
2Interleukin-6 (Interleukin 6)IBA
07/2008 - 05/2006
1DNA Transposable Elements (Element, IS)IBA
01/2020
1Protein Kinase D2IBA
11/2019
1Dizocilpine Maleate (Dizocilpine)IBA
11/2016
1Prostaglandin D2IBA
11/2016
1Cyclooxygenase 1IBA
11/2016
1Small Interfering RNA (siRNA)IBA
03/2016
1Hypoglycemic Agents (Hypoglycemics)IBA
01/2016
1DNA (Deoxyribonucleic Acid)IBA
01/2016
1Type I Vasoactive Intestinal Polypeptide ReceptorsIBA
01/2016
1DysbindinIBA
10/2014
1Neurotransmitter Agents (Neurotransmitter)IBA
10/2014
1prostaglandin D2 receptorIBA
02/2014
1MGS 0028IBA
02/2013
1Glutamic Acid (Glutamate)FDA Link
02/2013
1Serotonin (5 Hydroxytryptamine)IBA
11/2012
1Lurasidone HydrochlorideFDA Link
11/2012
1Risperidone (Risperdal Consta)FDA LinkGeneric
11/2012
1Neuroprotective AgentsIBA
11/2012
1Neuregulin-1 (Neuregulin 1)IBA
12/2010
1Retinaldehyde (Retinal)IBA
11/2010
1ErythropoietinFDA Link
11/2010
1ApelinIBA
11/2010
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2010
1salicylhydroxamic acid (SHAM)IBA
11/2010
1Oxygen (Dioxygen)IBA
11/2010
1Peptides (Polypeptides)IBA
11/2010
1Doxorubicin (Adriamycin)FDA LinkGeneric
06/2010
15-HT1A Serotonin ReceptorIBA
01/2010
1Lipase (Acid Lipase)FDA Link
08/2009
1AmylasesFDA Link
08/2009
1Methamphetamine (Desoxyn)FDA LinkGeneric
04/2009

Therapy/Procedure

1Therapeutics
11/2010
1Laparotomy
11/2010
1Lasers (Laser)
01/2010